I'm about to buy a 97 Regal 2100 LSR from the Tampa area. I intend to use
in fresh water. Is the salt-water use anything to be concerned about?

I agree, we need more info. Sal****er is BRUTAL. I'd get it
somewhere that it can be flushed so you can collect the water that
comes out of the engine. See what it looks like and look for rust,
scale, etc. in the water. Pull the plugs and make sure they look good
and also see what the oil looks like.