In an early application note for Transzorbs, the suppression
device was used on all electronic devices in the first DC-10.
An inaugural flight included Mayor Lindsay of NYC, V
President Agnew, and many other dignitaries - with much
champagne. But someone forgot to put transzorbs on the
electric toilets. The first flight was terminated early. Too
much champagne. No working toilets.

Ed Price wrote:
I agree completely; I regularly use Transzorbs on my 28 VDC military
designs. In mission critical (read that as flight controls or ordnance
systems), a combination of protection is used. For instance, something
like a transzorb, for quick clamping of a very fast risetime
transient. And a gas discharge tube, to handle a longer duration,
higher energy transient. And passive LC filtering too.
...