On Sun, 26 Feb 2017 08:09:47 -0500, Keyser Soze
wrote:

If I wanted a 1911 clone that fired .45 ACP, I'd get one. I don't like
the pistols or the rounds much. The.357 MAGs hit harder in self-defense
situations. If I were interested in the .45 ACP round, though, I'd
consider a dual load .45 revolver, like this Ruger Redhawk:

https://www.youtube.com/watch?v=dfcWPOecspQ

The problem is reliable feeding of a rimmed case in a semi auto.
Certainly there are guns that pull it off but the semi rim seems a lot
easier to feed. The flip side of that is the difficulty of chambering
a semi rim in a revolver without moon clips. Some will headspace off
the case neck but then they can be sensitive to ammo.